Mesenchymal Stem Cells Modified with a Single-Chain Antibody against EGFRvIII Successfully Inhibit the Growth of Human Xenograft Malignant Glioma

BACKGROUND: Glioblastoma multiforme is the most lethal brain tumor with limited therapeutic options. Antigens expressed on the surface of malignant cells are potential targets for antibody-mediated gene/drug delivery. PRINCIPAL FINDINGS: In this study, we investigated the ability of genetically modi...

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Detalles Bibliográficos
Autores principales: Balyasnikova, Irina V., Ferguson, Sherise D., Sengupta, Sadhak, Han, Yu, Lesniak, Maciej S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841188/
https://www.ncbi.nlm.nih.gov/pubmed/20305783
http://dx.doi.org/10.1371/journal.pone.0009750

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841188/
https://www.ncbi.nlm.nih.gov/pubmed/20305783
http://dx.doi.org/10.1371/journal.pone.0009750

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