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Cellular toxicity following application of adeno-associated viral vector-mediated RNA interference in the nervous system
BACKGROUND: After a spinal cord lesion, axon regeneration is inhibited by the presence of a diversity of inhibitory molecules in the lesion environment. At and around the lesion site myelin-associated inhibitors, chondroitin sulfate proteoglycans (CSPGs) and several axon guidance molecules, includin...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841193/ https://www.ncbi.nlm.nih.gov/pubmed/20167052 http://dx.doi.org/10.1186/1471-2202-11-20 |