SIRT3 regulates fatty acid oxidation via reversible enzyme deacetylation

Sirtuins are NAD(+)-dependent protein deacetylases and mediate adaptive responses to a variety of stresses, including calorie restriction and metabolic stress. Sirtuin 3 (SIRT3) is localized in the mitochondrial matrix where it regulates the acetylation levels of metabolic enzymes, including acetyl...

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Detalles Bibliográficos
Autores principales: Hirschey, Matthew D., Shimazu, Tadahiro, Goetzman, Eric, Jing, Enxuan, Schwer, Bjoern, Lombard, David B., Grueter, Carrie A., Harris, Charles, Biddinger, Sudha, Ilkayeva, Olga R., Stevens, Robert D., Li, Yu, Saha, Asish K., Ruderman, Neil B., Bain, James R., Newgard, Christopher B., Farese, Robert V., Alt, Frederick W., Kahn, C. Ronald, Verdin, Eric
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841477/
https://www.ncbi.nlm.nih.gov/pubmed/20203611
http://dx.doi.org/10.1038/nature08778

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841477/
https://www.ncbi.nlm.nih.gov/pubmed/20203611
http://dx.doi.org/10.1038/nature08778

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