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Gene expression profiling of cholangiocarcinoma-derived fibroblast reveals alterations related to tumor progression and indicates periostin as a poor prognostic marker

BACKGROUND: Fibroblasts play important roles in several cancers. It was hypothesized that cholangiocarcinoma (CCA)-associated fibroblasts (Cfs) differ from non-tumorigenic liver fibroblasts (Lfs) in their gene expression profiles resulting in the capability to promote cancer. Periostin (PN) is a mul...

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Detalles Bibliográficos
Autores principales: Utispan, Kusumawadee, Thuwajit, Peti, Abiko, Yoshimitsu, Charngkaew, Komgrid, Paupairoj, Anucha, Chau-in, Siri, Thuwajit, Chanitra
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841583/
https://www.ncbi.nlm.nih.gov/pubmed/20096135
http://dx.doi.org/10.1186/1476-4598-9-13