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Predicting Transmembrane Helix Packing Arrangements using Residue Contacts and a Force-Directed Algorithm

Alpha-helical transmembrane proteins constitute roughly 30% of a typical genome and are involved in a wide variety of important biological processes including cell signalling, transport of membrane-impermeable molecules and cell recognition. Despite significant efforts to predict transmembrane prote...

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Detalles Bibliográficos
Autores principales: Nugent, Timothy, Jones, David T.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841610/
https://www.ncbi.nlm.nih.gov/pubmed/20333233
http://dx.doi.org/10.1371/journal.pcbi.1000714