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Predicting Transmembrane Helix Packing Arrangements using Residue Contacts and a Force-Directed Algorithm
Alpha-helical transmembrane proteins constitute roughly 30% of a typical genome and are involved in a wide variety of important biological processes including cell signalling, transport of membrane-impermeable molecules and cell recognition. Despite significant efforts to predict transmembrane prote...
Autores principales: | Nugent, Timothy, Jones, David T. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841610/ https://www.ncbi.nlm.nih.gov/pubmed/20333233 http://dx.doi.org/10.1371/journal.pcbi.1000714 |
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