Differential Regulation of Effector- and Central-Memory Responses to Toxoplasma gondii Infection by IL-12 Revealed by Tracking of Tgd057-Specific CD8+ T Cells

Production of the pro-inflammatory cytokine IL-12 by innate phagocytes drives the differentiation of IFN-γ-producing effector T cells during Toxoplasma gondii infection. However, the role of IL-12 in the regulation of memory CD8+ T cell differentiation and function during murine toxoplasmosis is unc...

Descripción completa

Detalles Bibliográficos
Autores principales: Wilson, Douglas C., Grotenbreg, Gijsbert M., Liu, Kenian, Zhao, Yanlin, Frickel, Eva-Maria, Gubbels, Marc-Jan, Ploegh, Hidde L., Yap, George S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841619/
https://www.ncbi.nlm.nih.gov/pubmed/20333242
http://dx.doi.org/10.1371/journal.ppat.1000815

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841619/
https://www.ncbi.nlm.nih.gov/pubmed/20333242
http://dx.doi.org/10.1371/journal.ppat.1000815

Ejemplares similares