Tumor Growth Rate Determines the Timing of Optimal Chronomodulated Treatment Schedules

In host and cancer tissues, drug metabolism and susceptibility to drugs vary in a circadian (24 h) manner. In particular, the efficacy of a cell cycle specific (CCS) cytotoxic agent is affected by the daily modulation of cell cycle activity in the target tissues. Anti-cancer chronotherapy, in which...

Descripción completa

Detalles Bibliográficos
Autores principales: Bernard, Samuel, Čajavec Bernard, Branka, Lévi, Francis, Herzel, Hanspeter
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841621/
https://www.ncbi.nlm.nih.gov/pubmed/20333244
http://dx.doi.org/10.1371/journal.pcbi.1000712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841621/
https://www.ncbi.nlm.nih.gov/pubmed/20333244
http://dx.doi.org/10.1371/journal.pcbi.1000712

Ejemplares similares