Human Cytomegalovirus Protein pUL117 Targets the Mini-Chromosome Maintenance Complex and Suppresses Cellular DNA Synthesis

Modulation of host DNA synthesis is essential for many viruses to establish productive infections and contributes to viral diseases. Human cytomegalovirus (HCMV), a large DNA virus, blocks host DNA synthesis and deregulates cell cycle progression. We report that pUL117, a viral protein that we recen...

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Detalles Bibliográficos
Autores principales: Qian, Zhikang, Leung-Pineda, Van, Xuan, Baoqin, Piwnica-Worms, Helen, Yu, Dong
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841624/
https://www.ncbi.nlm.nih.gov/pubmed/20333247
http://dx.doi.org/10.1371/journal.ppat.1000814

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841624/
https://www.ncbi.nlm.nih.gov/pubmed/20333247
http://dx.doi.org/10.1371/journal.ppat.1000814

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