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Nucleophosmin Phosphorylation by v-Cyclin-CDK6 Controls KSHV Latency

Nucleophosmin (NPM) is a multifunctional nuclear phosphoprotein and a histone chaperone implicated in chromatin organization and transcription control. Oncogenic Kaposi's sarcoma herpesvirus (KSHV) is the etiological agent of Kaposi's sarcoma, primary effusion lymphoma (PEL) and multicentr...

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Detalles Bibliográficos
Autores principales: Sarek, Grzegorz, Järviluoma, Annika, Moore, Henna M., Tojkander, Sari, Vartia, Salla, Biberfeld, Peter, Laiho, Marikki, Ojala, Päivi M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841626/
https://www.ncbi.nlm.nih.gov/pubmed/20333249
http://dx.doi.org/10.1371/journal.ppat.1000818