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The Role of the Receptor for Advanced Glycation End-Products in a Murine Model of Silicosis

BACKGROUND: The role of the receptor for advanced glycation end-products (RAGE) has been shown to differ in two different mouse models of asbestos and bleomycin induced pulmonary fibrosis. RAGE knockout (KO) mice get worse fibrosis when challenged with asbestos, whereas in the bleomycin model they a...

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Detalles Bibliográficos
Autores principales: Ramsgaard, Lasse, Englert, Judson M., Tobolewski, Jacob, Tomai, Lauren, Fattman, Cheryl L., Leme, Adriana S., Kaynar, A. Murat, Shapiro, Steven D., Enghild, Jan J., Oury, Tim D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841632/
https://www.ncbi.nlm.nih.gov/pubmed/20333255
http://dx.doi.org/10.1371/journal.pone.0009604