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Cleft Palate Is Caused by CNS Dysfunction in Gad1 and Viaat Knockout Mice
BACKGROUND: Previous studies have shown that disruption of GABA signaling in mice via mutations in the Gad1, Gabrb3 or Viaat genes leads to the development of non-neural developmental defects such as cleft palate. Studies of the Gabrb3 and Gad1 mutant mice have suggested that GABA function could be...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841638/ https://www.ncbi.nlm.nih.gov/pubmed/20333300 http://dx.doi.org/10.1371/journal.pone.0009758 |