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Cleft Palate Is Caused by CNS Dysfunction in Gad1 and Viaat Knockout Mice

BACKGROUND: Previous studies have shown that disruption of GABA signaling in mice via mutations in the Gad1, Gabrb3 or Viaat genes leads to the development of non-neural developmental defects such as cleft palate. Studies of the Gabrb3 and Gad1 mutant mice have suggested that GABA function could be...

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Detalles Bibliográficos
Autores principales: Oh, Won-Jong, Westmoreland, Joby J., Summers, Ryan, Condie, Brian G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841638/
https://www.ncbi.nlm.nih.gov/pubmed/20333300
http://dx.doi.org/10.1371/journal.pone.0009758