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3D Analysis of the TCR/pMHCII Complex Formation in Monkeys Vaccinated with the First Peptide Inducing Sterilizing Immunity against Human Malaria

T-cell receptor gene rearrangements were studied in Aotus monkeys developing high antibody titers and sterilizing immunity against the Plasmodium falciparum malaria parasite upon vaccination with the modified synthetic peptide 24112, which was identified in the Merozoite Surface Protein 2 (MSP-2) an...

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Detalles Bibliográficos
Autores principales: Patarroyo, Manuel A., Bermúdez, Adriana, López, Carolina, Yepes, Gloria, Patarroyo, Manuel E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841639/
https://www.ncbi.nlm.nih.gov/pubmed/20333301
http://dx.doi.org/10.1371/journal.pone.0009771