Cargando…
3D Analysis of the TCR/pMHCII Complex Formation in Monkeys Vaccinated with the First Peptide Inducing Sterilizing Immunity against Human Malaria
T-cell receptor gene rearrangements were studied in Aotus monkeys developing high antibody titers and sterilizing immunity against the Plasmodium falciparum malaria parasite upon vaccination with the modified synthetic peptide 24112, which was identified in the Merozoite Surface Protein 2 (MSP-2) an...
Autores principales: | Patarroyo, Manuel A., Bermúdez, Adriana, López, Carolina, Yepes, Gloria, Patarroyo, Manuel E. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841639/ https://www.ncbi.nlm.nih.gov/pubmed/20333301 http://dx.doi.org/10.1371/journal.pone.0009771 |
Ejemplares similares
-
Reciprocal TCR-CD3 and CD4 Engagement of a Nucleating pMHCII Stabilizes a Functional Receptor Macrocomplex
por: Glassman, Caleb R., et al.
Publicado: (2018) -
The CD4 transmembrane GGXXG and juxtamembrane (C/F)CV+C motifs mediate pMHCII-specific signaling independently of CD4-Lck interactions
por: Lee, Mark S., et al.
Publicado: (2023) -
Specific β-Turns Precede PPII(L) Structures Binding to Allele-Specific HLA-DRβ1(*) PBRs in Fully-Protective Malaria Vaccine Components
por: Bermudez, Adriana, et al.
Publicado: (2018) -
Identification and Diversity of Killer Cell Ig-Like Receptors in Aotus vociferans, a New World Monkey
por: Garzón-Ospina, Diego, et al.
Publicado: (2013) -
The First Chemically-Synthesised, Highly Immunogenic Anti-SARS-CoV-2 Peptides in DNA Genotyped Aotus Monkeys for Human Use
por: Patarroyo, Manuel E., et al.
Publicado: (2021)