A modified hTERT Promoter-directed Oncolytic Adenovirus Replication with Concurrent Inhibition of TGFβ Signaling for Breast Cancer Therapy

Our laboratory is interested to develop oncolytic adenoviral vectors that can be administered systemically for the treatment of breast cancer. To restrict viral replication in breast tumor cells, we have constructed mhTERTAd.sTβRFc, a 01/07 based adenoviral vector expressing the soluble form of TGFβ...

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Detalles Bibliográficos
Autores principales: Hu, Zebin, Robbins, John S., Pister, Amanda, Zafar, M. Behzad, Zhang, Zhen-Wei, Gupta, Janhavi, Lee, K. Jessica, Neuman, Kam, Yun, Chae-Ok, Guise, Theresa, Seth, Prem
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841698/
https://www.ncbi.nlm.nih.gov/pubmed/19798122
http://dx.doi.org/10.1038/cgt.2009.72

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841698/
https://www.ncbi.nlm.nih.gov/pubmed/19798122
http://dx.doi.org/10.1038/cgt.2009.72

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