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Regression of murine lung tumors by the let-7 microRNA

MicroRNAs (miRNAs) have recently emerged as an important new class of cellular regulators that control various cellular processes and are implicated in human diseases, including cancer. Here, we show that loss of let-7 function enhances lung tumor formation in vivo, strongly supporting the hypothesi...

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Detalles Bibliográficos
Autores principales: Trang, Phong, Medina, Pedro P., Wiggins, Jason F., Ruffino, Lynnsie, Kelnar, Kevin, Omotola, Michael, Homer, Robert, Brown, David, Bader, Andreas G., Weidhaas, Joanne B., Slack, Frank J.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841713/
https://www.ncbi.nlm.nih.gov/pubmed/19966857
http://dx.doi.org/10.1038/onc.2009.445