Protein Modification, Bioconjugation, and Disulfide Bridging Using Bromomaleimides

[Image: see text] The maleimide motif is widely used for the selective chemical modification of cysteine residues in proteins. Despite widespread utilization, there are some potential limitations, including the irreversible nature of the reaction and, hence, the modification and the number of attach...

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Detalles Bibliográficos
Autores principales: Smith, Mark E. B., Schumacher, Felix F., Ryan, Chris P., Tedaldi, Lauren M., Papaioannou, Danai, Waksman, Gabriel, Caddick, Stephen, Baker, James R.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2010
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842020/
https://www.ncbi.nlm.nih.gov/pubmed/20092331
http://dx.doi.org/10.1021/ja908610s

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842020/
https://www.ncbi.nlm.nih.gov/pubmed/20092331
http://dx.doi.org/10.1021/ja908610s

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