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Protein Modification, Bioconjugation, and Disulfide Bridging Using Bromomaleimides
[Image: see text] The maleimide motif is widely used for the selective chemical modification of cysteine residues in proteins. Despite widespread utilization, there are some potential limitations, including the irreversible nature of the reaction and, hence, the modification and the number of attach...
Autores principales: | Smith, Mark E. B., Schumacher, Felix F., Ryan, Chris P., Tedaldi, Lauren M., Papaioannou, Danai, Waksman, Gabriel, Caddick, Stephen, Baker, James R. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842020/ https://www.ncbi.nlm.nih.gov/pubmed/20092331 http://dx.doi.org/10.1021/ja908610s |
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