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The promyelocytic leukemia zinc finger gene, PLZF, is frequently downregulated in malignant mesothelioma cells and contributes to cell survival

DNA copy number analysis was performed, using SNP mapping arrays, to fine map genomic imbalances in human malignant mesothelioma (MM) cell lines derived from primary tumors. Chromosomal losses accounted for the majority of genomic imbalances. All 22 cell lines examined showed homozygous deletions of...

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Detalles Bibliográficos
Autores principales: Cheung, Mitchell, Pei, Jianming, Pei, Yaguang, Jhanwar, Suresh C., Pass, Harvey I., Testa, Joseph R.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842080/
https://www.ncbi.nlm.nih.gov/pubmed/20010871
http://dx.doi.org/10.1038/onc.2009.455