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Effect of MDM2 SNP309 and p53 codon 72 polymorphisms on lung cancer risk and survival among non-smoking Chinese women in Singapore

BACKGROUND: Single nucleotide polymorphism (SNP) 309 resulting in a T or G allele in the promoter of MDM2, the negative regulator of p53, has been suggested to affect cancer predisposition and age of onset, primarily in females. However, findings have been inconsistent in various cancers, and ethnic...

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Detalles Bibliográficos
Autores principales: Chua, Hui Wan, Ng, Daniel, Choo, Serena, Lum, San San, Li, Huihua, Soh, Li Ying, Sabapathy, Kanaga, Seow, Adeline
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842241/
https://www.ncbi.nlm.nih.gov/pubmed/20219101
http://dx.doi.org/10.1186/1471-2407-10-88