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Effect of MDM2 SNP309 and p53 codon 72 polymorphisms on lung cancer risk and survival among non-smoking Chinese women in Singapore
BACKGROUND: Single nucleotide polymorphism (SNP) 309 resulting in a T or G allele in the promoter of MDM2, the negative regulator of p53, has been suggested to affect cancer predisposition and age of onset, primarily in females. However, findings have been inconsistent in various cancers, and ethnic...
Autores principales: | Chua, Hui Wan, Ng, Daniel, Choo, Serena, Lum, San San, Li, Huihua, Soh, Li Ying, Sabapathy, Kanaga, Seow, Adeline |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842241/ https://www.ncbi.nlm.nih.gov/pubmed/20219101 http://dx.doi.org/10.1186/1471-2407-10-88 |
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