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Unified translation repression mechanism for microRNAs and upstream AUGs

BACKGROUND: MicroRNAs (miRNAs) are endogenous small RNAs that modulate gene expression at the post-transcriptional level by binding complementary sites in the 3'-UTR. In a recent genome-wide study reporting a new miRNA target class (miBridge), we identified and validated interactions between 5&...

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Detalles Bibliográficos
Autores principales: Ajay, Subramanian S, Athey, Brian D, Lee, Inhan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842251/
https://www.ncbi.nlm.nih.gov/pubmed/20205738
http://dx.doi.org/10.1186/1471-2164-11-155