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A Live Zebrafish-Based Screening System for Human Nuclear Receptor Ligand and Cofactor Discovery

Nuclear receptors (NRs) belong to a superfamily of transcription factors that regulate numerous homeostatic, metabolic and reproductive processes. Taken together with their modulation by small lipophilic molecules, they also represent an important and successful class of drug targets. Although many...

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Detalles Bibliográficos
Autores principales: Tiefenbach, Jens, Moll, Pamela R., Nelson, Meryl R., Hu, Chun, Baev, Lilia, Kislinger, Thomas, Krause, Henry M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842432/
https://www.ncbi.nlm.nih.gov/pubmed/20339547
http://dx.doi.org/10.1371/journal.pone.0009797