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A Live Zebrafish-Based Screening System for Human Nuclear Receptor Ligand and Cofactor Discovery
Nuclear receptors (NRs) belong to a superfamily of transcription factors that regulate numerous homeostatic, metabolic and reproductive processes. Taken together with their modulation by small lipophilic molecules, they also represent an important and successful class of drug targets. Although many...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842432/ https://www.ncbi.nlm.nih.gov/pubmed/20339547 http://dx.doi.org/10.1371/journal.pone.0009797 |