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2′-5′-Oligoadenylate synthetase single-nucleotide polymorphisms and haplotypes are associated with variations in immune responses to rubella vaccine

Interferon-induced antiviral genes are crucial players in innate antiviral defense and potential determinants of immune response heterogeneity. We selected 114 candidate single-nucleotide polymorphisms (SNPs) from 12 antiviral genes using an LD tagSNP selection approach and genotyped them in a cohor...

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Detalles Bibliográficos
Autores principales: Haralambieva, Iana H., Dhiman, Neelam, Ovsyannikova, Inna G., Vierkant, Robert A., Pankratz, V. Shane, Jacobson, Robert M., Poland, Gregory A.
Formato: Texto
Lenguaje:English
Publicado: American Society for Histocompatibility and Immunogenetics. Published by Elsevier Inc. 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842477/
https://www.ncbi.nlm.nih.gov/pubmed/20079393
http://dx.doi.org/10.1016/j.humimm.2010.01.004