Secreted Semaphorins Control Spine Distribution and Morphogenesis in the Postnatal CNS

The majority of excitatory synapses in the mammalian CNS are formed on dendritic spines1, and spine morphology and distribution are critical for synaptic transmission2–6, synaptic integration and plasticity7. Here, we show that a secreted semaphorin, Sema3F, is a negative regulator of spine developm...

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Detalles Bibliográficos
Autores principales: Tran, Tracy S., Rubio, Maria E., Clem, Roger L., Johnson, Dontais, Case, Lauren, Tessier-Lavigne, Marc, Huganir, Richard L., Ginty, David D., Kolodkin, Alex L.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842559/
https://www.ncbi.nlm.nih.gov/pubmed/20010807
http://dx.doi.org/10.1038/nature08628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842559/
https://www.ncbi.nlm.nih.gov/pubmed/20010807
http://dx.doi.org/10.1038/nature08628

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