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Partial hexokinase II knockout results in acute ischemia–reperfusion damage in skeletal muscle of male, but not female, mice

Cellular studies have demonstrated a protective role of mitochondrial hexokinase against oxidative insults. It is unknown whether HK protective effects translate to the in vivo condition. In the present study, we hypothesize that HK affects acute ischemia–reperfusion injury in skeletal muscle of the...

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Detalles Bibliográficos
Autores principales: Smeele, Kirsten M., Eerbeek, Otto, Koeman, Anneke, Bezemer, Rick, Ince, Can, Heikkinen, Sami, Laakso, Markku, de Haan, Arnold, Schaart, Gert, Drost, Maarten R., Hollmann, Markus W., Zuurbier, Coert J.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842566/
https://www.ncbi.nlm.nih.gov/pubmed/20182739
http://dx.doi.org/10.1007/s00424-010-0787-3