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Partial hexokinase II knockout results in acute ischemia–reperfusion damage in skeletal muscle of male, but not female, mice
Cellular studies have demonstrated a protective role of mitochondrial hexokinase against oxidative insults. It is unknown whether HK protective effects translate to the in vivo condition. In the present study, we hypothesize that HK affects acute ischemia–reperfusion injury in skeletal muscle of the...
Autores principales: | Smeele, Kirsten M., Eerbeek, Otto, Koeman, Anneke, Bezemer, Rick, Ince, Can, Heikkinen, Sami, Laakso, Markku, de Haan, Arnold, Schaart, Gert, Drost, Maarten R., Hollmann, Markus W., Zuurbier, Coert J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842566/ https://www.ncbi.nlm.nih.gov/pubmed/20182739 http://dx.doi.org/10.1007/s00424-010-0787-3 |
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