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Aerosol Infection Model of Tuberculosis in Wistar Rats

We explored suitability of a rat tuberculosis aerosol infection model for investigating the pharmacodynamics of new antimycobacterial agents. Infection of rats via the aerosol route led to a reproducible course of M. tuberculosis infection in the lungs. The pulmonary bacterial load increased logarit...

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Detalles Bibliográficos
Autores principales: Gaonkar, Sheshagiri, Bharath, Sowmya, Kumar, Naveen, Balasubramanian, V., Shandil, Radha K.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842889/
https://www.ncbi.nlm.nih.gov/pubmed/20339504
http://dx.doi.org/10.1155/2010/426035