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Identification of an MSI-H Tumor-Specific Cytotoxic T Cell Epitope Generated by the (−1) Frame of U79260(FTO)

Microsatellite instability (MSI-H) induced by defects of the DNA mismatch repair system results in insertion or deletion of single nucleotides at short repetitive DNA sequences. About 15% of sporadic and approximately 90% of hereditary nonpolyposis colorectal cancers display MSI-H. When affecting co...

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Detalles Bibliográficos
Autores principales: Linnebacher, Michael, Wienck, Anne, Boeck, Inga, Klar, Ernst
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842904/
https://www.ncbi.nlm.nih.gov/pubmed/20339516
http://dx.doi.org/10.1155/2010/841451