Evidence of STAT5 dependent and independent routes to CD8 memory formation and a preferential role for IL-7 over IL-15 in STAT5 activation

IL-7 and IL-15 have non-redundant roles in promoting development of memory CD8(+) T cells. STAT5 is activated by receptors of both cytokines and has also been implicated as a requirement for generation of memory. To determine whether STAT5 activity was required for IL-7 and IL-15-mediated generation...

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Detalles Bibliográficos
Autores principales: Kemp, Roslyn A, Pearson, Claire F, Cornish, Georgina H, Seddon, Benedict P
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842934/
https://www.ncbi.nlm.nih.gov/pubmed/19949423
http://dx.doi.org/10.1038/icb.2009.95

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842934/
https://www.ncbi.nlm.nih.gov/pubmed/19949423
http://dx.doi.org/10.1038/icb.2009.95

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