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Caffeine and a selective adenosine A(2A )receptor antagonist induce sensitization and cross-sensitization behavior associated with increased striatal dopamine in mice
BACKGROUND: Caffeine, a nonselective adenosine A(1 )and A(2A )receptor antagonist, is the most widely used psychoactive substance in the world. Evidence demonstrates that caffeine and selective adenosine A(2A )antagonists interact with the neuronal systems involved in drug reinforcement, locomotor s...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843608/ https://www.ncbi.nlm.nih.gov/pubmed/20074377 http://dx.doi.org/10.1186/1423-0127-17-4 |