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Caffeine and a selective adenosine A(2A )receptor antagonist induce sensitization and cross-sensitization behavior associated with increased striatal dopamine in mice

BACKGROUND: Caffeine, a nonselective adenosine A(1 )and A(2A )receptor antagonist, is the most widely used psychoactive substance in the world. Evidence demonstrates that caffeine and selective adenosine A(2A )antagonists interact with the neuronal systems involved in drug reinforcement, locomotor s...

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Detalles Bibliográficos
Autores principales: Hsu, Chih W, Wang, Chin S, Chiu, Ted H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843608/
https://www.ncbi.nlm.nih.gov/pubmed/20074377
http://dx.doi.org/10.1186/1423-0127-17-4