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Protein engineering of conger eel galectins by tracing of molecular evolution using probable ancestral mutants

BACKGROUND: Conger eel galectins, congerin I (ConI) and congerin II (ConII), show the different molecular characteristics resulting from accelerating evolution. We recently reconstructed a probable ancestral form of congerins, Con-anc. It showed properties similar to those of ConII in terms of therm...

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Detalles Bibliográficos
Autores principales: Konno, Ayumu, Yonemaru, Shintarou, Kitagawa, Atsushi, Muramoto, Koji, Shirai, Tsuyoshi, Ogawa, Tomohisa
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843614/
https://www.ncbi.nlm.nih.gov/pubmed/20152053
http://dx.doi.org/10.1186/1471-2148-10-43