The type I insulin-like growth factor receptor regulates cancer metastasis independently of primary tumor growth by promoting invasion and survival

The type I insulin-like growth factor receptor (IGF1R) regulates multiple aspects of malignancy and is the target of several drugs currently in clinical trials. While IGF1R’s role in proliferation and survival is well-studied, the regulation of metastasis by IGF1R is not as clearly delineated. Previ...

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Detalles Bibliográficos
Autores principales: Sachdev, Deepali, Zhang, Xihong, Matise, Ilze, Gaillard-Kelly, Martine, Yee, Douglas
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843625/
https://www.ncbi.nlm.nih.gov/pubmed/19838209
http://dx.doi.org/10.1038/onc.2009.316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843625/
https://www.ncbi.nlm.nih.gov/pubmed/19838209
http://dx.doi.org/10.1038/onc.2009.316

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