Cargando…
The type I insulin-like growth factor receptor regulates cancer metastasis independently of primary tumor growth by promoting invasion and survival
The type I insulin-like growth factor receptor (IGF1R) regulates multiple aspects of malignancy and is the target of several drugs currently in clinical trials. While IGF1R’s role in proliferation and survival is well-studied, the regulation of metastasis by IGF1R is not as clearly delineated. Previ...
Autores principales: | Sachdev, Deepali, Zhang, Xihong, Matise, Ilze, Gaillard-Kelly, Martine, Yee, Douglas |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843625/ https://www.ncbi.nlm.nih.gov/pubmed/19838209 http://dx.doi.org/10.1038/onc.2009.316 |
Ejemplares similares
-
Tyrosine kinase signalling in breast cancer: Insulin-like growth factors and their receptors in breast cancer
por: Zhang, Xihong, et al.
Publicado: (2000) -
Inhibition of Cancer Cell Proliferation and Metastasis by Insulin Receptor Downregulation
por: Zhang, Hua, et al.
Publicado: (2010) -
Insulin-like growth factor-I receptor activity is essential for Kaposi's sarcoma growth and survival
por: Catrina, S-B, et al.
Publicado: (2005) -
Targeting insulin-like growth factor pathways
por: Yee, D
Publicado: (2006) -
Targeting Insulin-Like Growth Factor 1 Receptor Inhibits Pancreatic Cancer Growth and Metastasis
por: Subramani, Ramadevi, et al.
Publicado: (2014)