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HIV-1 Fusion Inhibitor Peptides Enfuvirtide and T-1249 Interact with Erythrocyte and Lymphocyte Membranes

Enfuvirtide and T-1249 are two HIV-1 fusion inhibitor peptides that bind to gp41 and prevent its fusogenic conformation, inhibiting viral entry into host cells. Previous studies established the relative preferences of these peptides for membrane model systems of defined lipid compositions. We aimed...

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Detalles Bibliográficos
Autores principales: Matos, Pedro M., Castanho, Miguel A. R. B., Santos, Nuno C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843717/
https://www.ncbi.nlm.nih.gov/pubmed/20352107
http://dx.doi.org/10.1371/journal.pone.0009830