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Incorporating prior knowledge to facilitate discoveries in a genome-wide association study on age-related macular degeneration
BACKGROUND: Substantial genotyping data produced by current high-throughput technologies have brought opportunities and difficulties. With the number of single-nucleotide polymorphisms (SNPs) going into millions comes the harsh challenge of multiple-testing adjustment. However, even with the false d...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843735/ https://www.ncbi.nlm.nih.gov/pubmed/20181037 http://dx.doi.org/10.1186/1756-0500-3-26 |