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Stress-Induced Sphingolipid Signaling: Role of Type-2 Neutral Sphingomyelinase in Murine Cell Apoptosis and Proliferation

BACKGROUND: Sphingomyelin hydrolysis in response to stress-inducing agents, and subsequent ceramide generation, are implicated in various cellular responses, including apoptosis, inflammation and proliferation, depending on the nature of the different acidic or neutral sphingomyelinases. This study...

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Detalles Bibliográficos
Autores principales: Devillard, Raphael, Galvani, Sylvain, Thiers, Jean-Claude, Guenet, Jean-Louis, Hannun, Yusuf, Bielawski, Jacek, Nègre-Salvayre, Anne, Salvayre, Robert, Augé, Nathalie
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843740/
https://www.ncbi.nlm.nih.gov/pubmed/20352118
http://dx.doi.org/10.1371/journal.pone.0009826