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Cyclosporine Inhibits a Direct Interaction between Cyclophilins and Hepatitis C NS5A

BACKGROUND: Hepatitis C Virus (HCV) infection is a leading indication for liver transplantation. HCV infection reoccurs almost universally post transplant, decreasing both graft longevity and patient survival. The immunosuppressant, cyclosporine A (CsA) has potent anti-HCV activity towards both HCV...

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Detalles Bibliográficos
Autores principales: Fernandes, Fiona, Ansari, Israr-ul H., Striker, Rob
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843741/
https://www.ncbi.nlm.nih.gov/pubmed/20352119
http://dx.doi.org/10.1371/journal.pone.0009815