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Cyclosporine Inhibits a Direct Interaction between Cyclophilins and Hepatitis C NS5A
BACKGROUND: Hepatitis C Virus (HCV) infection is a leading indication for liver transplantation. HCV infection reoccurs almost universally post transplant, decreasing both graft longevity and patient survival. The immunosuppressant, cyclosporine A (CsA) has potent anti-HCV activity towards both HCV...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843741/ https://www.ncbi.nlm.nih.gov/pubmed/20352119 http://dx.doi.org/10.1371/journal.pone.0009815 |