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Transient Tumor-Fibroblast Interactions Increase Tumor Cell Malignancy by a TGF-β Mediated Mechanism in a Mouse Xenograft Model of Breast Cancer

Carcinoma are complex societies of mutually interacting cells in which there is a progressive failure of normal homeostatic mechanisms, causing the parenchymal component to expand inappropriately and ultimately to disseminate to distant sites. When a cancer cell metastasizes, it first will be expose...

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Detalles Bibliográficos
Autores principales: Stuelten, Christina H., Busch, Johanna I., Tang, Binwu, Flanders, Kathleen C., Oshima, Akira, Sutton, Emily, Karpova, Tatiana S., Roberts, Anita B., Wakefield, Lalage M., Niederhuber, John E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843748/
https://www.ncbi.nlm.nih.gov/pubmed/20352126
http://dx.doi.org/10.1371/journal.pone.0009832