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Transient Tumor-Fibroblast Interactions Increase Tumor Cell Malignancy by a TGF-β Mediated Mechanism in a Mouse Xenograft Model of Breast Cancer
Carcinoma are complex societies of mutually interacting cells in which there is a progressive failure of normal homeostatic mechanisms, causing the parenchymal component to expand inappropriately and ultimately to disseminate to distant sites. When a cancer cell metastasizes, it first will be expose...
Autores principales: | Stuelten, Christina H., Busch, Johanna I., Tang, Binwu, Flanders, Kathleen C., Oshima, Akira, Sutton, Emily, Karpova, Tatiana S., Roberts, Anita B., Wakefield, Lalage M., Niederhuber, John E. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843748/ https://www.ncbi.nlm.nih.gov/pubmed/20352126 http://dx.doi.org/10.1371/journal.pone.0009832 |
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