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M1T1 group A streptococcal pili promote epithelial colonization but diminish systemic virulence through neutrophil extracellular entrapment

Group A Streptococcus is a leading human pathogen associated with a diverse array of mucosal and systemic infections. Cell wall anchored pili were recently described in several species of pathogenic streptococci, and in the case of GAS, these surface appendages were demonstrated to facilitate epithe...

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Detalles Bibliográficos
Autores principales: Crotty Alexander, Laura E., Maisey, Heather C., Timmer, Anjuli M., Rooijakkers, Suzan H. M., Gallo, Richard L., von Köckritz-Blickwede, Maren, Nizet, Victor
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843839/
https://www.ncbi.nlm.nih.gov/pubmed/19960175
http://dx.doi.org/10.1007/s00109-009-0566-9