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M1T1 group A streptococcal pili promote epithelial colonization but diminish systemic virulence through neutrophil extracellular entrapment
Group A Streptococcus is a leading human pathogen associated with a diverse array of mucosal and systemic infections. Cell wall anchored pili were recently described in several species of pathogenic streptococci, and in the case of GAS, these surface appendages were demonstrated to facilitate epithe...
Autores principales: | Crotty Alexander, Laura E., Maisey, Heather C., Timmer, Anjuli M., Rooijakkers, Suzan H. M., Gallo, Richard L., von Köckritz-Blickwede, Maren, Nizet, Victor |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843839/ https://www.ncbi.nlm.nih.gov/pubmed/19960175 http://dx.doi.org/10.1007/s00109-009-0566-9 |
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