MutSβ exceeds MutSα in dinucleotide loop repair

BACKROUND: The target substrates of DNA mismatch recognising factors MutSα (MSH2+MSH6) and MutSβ (MSH2+MSH3) have already been widely researched. However, the extent of their functional redundancy and clinical substance remains unclear. Mismatch repair (MMR)-deficient tumours are strongly associated...

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Detalles Bibliográficos
Autores principales: Kantelinen, J, Kansikas, M, Korhonen, M K, Ollila, S, Heinimann, K, Kariola, R, Nyström, M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2844022/
https://www.ncbi.nlm.nih.gov/pubmed/20160730
http://dx.doi.org/10.1038/sj.bjc.6605531

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2844022/
https://www.ncbi.nlm.nih.gov/pubmed/20160730
http://dx.doi.org/10.1038/sj.bjc.6605531

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