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High frequency of β-catenin heterozygous mutations in extra-abdominal fibromatosis: a potential molecular tool for disease management

BACKGROUND: Fibromatosis comprises distinct clinical entities, including sporadic extra-abdominal fibromatosis, which have a high tendency for recurrence, even after adequate resection. There are no known molecular biomarkers of local recurrence. We searched for β-catenin mutations in a European mul...

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Detalles Bibliográficos
Autores principales: Dômont, J, Salas, S, Lacroix, L, Brouste, V, Saulnier, P, Terrier, P, Ranchère, D, Neuville, A, Leroux, A, Guillou, L, Sciot, R, Collin, F, Dufresne, A, Blay, J-Y, Le Cesne, A, Coindre, J-M, Bonvalot, S, Bénard, J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2844024/
https://www.ncbi.nlm.nih.gov/pubmed/20197769
http://dx.doi.org/10.1038/sj.bjc.6605557