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8-Hydroxydeoxyguanosine: a new potential independent prognostic factor in breast cancer

BACKGROUND: 8-Hydroxydeoxyguanosine (8-oxodG) is the commonly used marker of oxidative stress-derived DNA damage. 8-OxodG formation is regulated by local antioxidant capacity and DNA repair enzyme activity. Earlier studies have reported contradictory data on the function of 8-oxodG as a prognostic f...

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Detalles Bibliográficos
Autores principales: Sova, H, Jukkola-Vuorinen, A, Puistola, U, Kauppila, S, Karihtala, P
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2844025/
https://www.ncbi.nlm.nih.gov/pubmed/20179711
http://dx.doi.org/10.1038/sj.bjc.6605565