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Deficiency in APOBEC2 Leads to a Shift in Muscle Fiber Type, Diminished Body Mass, and Myopathy

The apoB RNA-editing enzyme, catalytic polypeptide-like (APOBEC) family of proteins includes APOBEC1, APOBEC3, and activation-induced deaminase, all of which are zinc-dependent cytidine deaminases active on polynucleotides and involved in RNA editing or DNA mutation. In contrast, the biochemical and...

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Detalles Bibliográficos
Autores principales: Sato, Yusuke, Probst, Hans Christian, Tatsumi, Ryuichi, Ikeuchi, Yoshihide, Neuberger, Michael S., Rada, Cristina
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2844160/
https://www.ncbi.nlm.nih.gov/pubmed/20022958
http://dx.doi.org/10.1074/jbc.M109.052977