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Distinct and Histone-Specific Modifications Mediate Positive versus Negative Transcriptional Regulation of TSHα Promoter

BACKGROUND: Hormonally-regulated histone modifications that govern positive versus negative transcription of target genes are poorly characterized despite their importance for normal and pathological endocrine function. There have been only a few studies examining chromatin modifications on target g...

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Detalles Bibliográficos
Autores principales: Wang, Dongqing, Xia, Xianmin, Weiss, Roy E., Refetoff, Samuel, Yen, Paul M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2844428/
https://www.ncbi.nlm.nih.gov/pubmed/20352046
http://dx.doi.org/10.1371/journal.pone.0009853