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Distinct and Histone-Specific Modifications Mediate Positive versus Negative Transcriptional Regulation of TSHα Promoter
BACKGROUND: Hormonally-regulated histone modifications that govern positive versus negative transcription of target genes are poorly characterized despite their importance for normal and pathological endocrine function. There have been only a few studies examining chromatin modifications on target g...
Autores principales: | Wang, Dongqing, Xia, Xianmin, Weiss, Roy E., Refetoff, Samuel, Yen, Paul M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2844428/ https://www.ncbi.nlm.nih.gov/pubmed/20352046 http://dx.doi.org/10.1371/journal.pone.0009853 |
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