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Delayed kinetics of poliovirus RNA synthesis in a human cell line with reduced levels of hnRNP C proteins

The hnRNP C heterotetramer [(C1(3))C2] binds RNA polymerase II transcripts in the nucleus, along with other proteins of the core hnRNP complex, and plays an important role in mRNA biogenesis and transport. Infection of HeLa cells with poliovirus causes hnRNP C to re-localize from the nucleus, where...

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Detalles Bibliográficos
Autores principales: Brunner, Jo Ellen, Ertel, Kenneth J., Rozovics, Janet M., Semler, Bert L.
Formato: Texto
Lenguaje:English
Publicado: Elsevier Inc. 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2844484/
https://www.ncbi.nlm.nih.gov/pubmed/20189623
http://dx.doi.org/10.1016/j.virol.2010.01.031